DIETARY POLYDEXTROSE INCREASES CALCIUM ABSORPTION IN NORMAL RATS Polidextrose aumenta a absorção de cálcio em ratos

نویسندگان

  • Elisvânia Freitas dos SANTOS
  • Kathia Hitomi TSUBOI
  • Marina Rachel ARAÚJO
  • Arthur C. OUWEHAND
  • Nelson Adami ANDREOLLO
  • Celio Kenji MIYASAKA
چکیده

Extensive gastric surgery is known to cause bone disorders (osteomalacia/osteoporosis)7,9 possibly related to an impaired capacity for the absorption of dietary calcium1,5. The absence of gastric acid after gastric resection may impair bioavailability of insoluble dietary calcium because gastric acid is the most important factor for solubilization of otherwise insoluble calcium salts5. The stomach plays an important role in calcium homeostasis, but the mechanism of gastric action is not yet completely understood. Recently, there have been several reports indicating that indigestible carbohydrates, such fructooligosaccharides10,11, inulin14, partially hydrolysed guar gum4 and polydextrose5, stimulate mineral absorption. Fiber is an essential nutrient in a healthy diet, contributing to health maintenance and preventing the occurrence of different disease. Polydextrose is a soluble fiber that is not digested in the upper gastrointestinal tract3. Beneficial bifidogenic and fiber-like effects of polydextrose have been previously demonstrated in humans6. The effects of polydextrose on mineral absorption have been little evaluated. The ingestion of the polydextrose on calcium absorption was only evaluated in the total-gastrectomized rats5. Therefore, the aim of current study was to examine effects of feeding polydextrose on calcium absorption and bone mineralization of normal and partially gastrectomized rats.

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تاریخ انتشار 2010